Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce is a delightful dish that brings together the rich flavors of garlic and Cajun spices with tender beef and creamy cheese. This recipe is perfect for family dinners, gatherings, or when you simply want a comforting meal that delivers on taste. With its creamy texture and bold flavors, this dish is sure to impress.
Why You’ll Love This Recipe
- Quick to Prepare: Ready in just 30 minutes, this recipe is perfect for busy weeknights.
- Flavor Explosion: The combination of garlic butter and Cajun seasoning creates a mouthwatering sauce that coats every bite.
- Cheesy Goodness: Velveeta, mozzarella, and Parmesan cheeses come together for a velvety texture that everyone will love.
- Versatile Dish: Great for any occasion—serve it at family dinners, potlucks, or casual get-togethers.
- Easily Customizable: Feel free to add your favorite vegetables or swap out the beef for turkey or chicken.
Tools and Preparation
Before diving into the cooking process, gather your tools. Having everything ready will make your cooking experience smoother and more enjoyable.
Essential Tools and Equipment
- Large pot
- Skillet
- Spatula
- Knife
- Cutting board
Importance of Each Tool
- Large pot: Essential for boiling the penne pasta perfectly to al dente.
- Skillet: Key for sautéing garlic and browning beef while creating the flavorful sauce.
- Spatula: Helps in breaking up the beef and mixing ingredients thoroughly.

Ingredients
For the Beef
- 1 lb ground beef
- 2 tablespoons butter
- 4 cloves garlic, minced
- 1 tablespoon Cajun seasoning
- 1 teaspoon Italian seasoning (optional but recommended)
For the Pasta
- 12 oz penne pasta
For the Sauce
- 1 cup heavy cream
- 1 cup Velveeta cheese, cubed
- 1 cup shredded mozzarella cheese
- ½ cup grated Parmesan cheese
- Salt and black pepper to taste
For Garnish (Optional)
- Fresh parsley
How to Make Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
Step 1: Cook the Pasta
Bring a large pot of salted water to a boil. Cook the penne pasta according to package directions until al dente. Drain and set aside.
Step 2: Sauté Garlic
In a large skillet over medium heat, melt the butter. Add the minced garlic and sauté for 1 minute until fragrant.
Step 3: Brown the Beef
Add the ground beef to the skillet. Cook until browned and fully cooked, breaking it up with a spatula. Drain any excess fat.
Step 4: Season the Meat
Sprinkle the Cajun seasoning and Italian seasoning over the beef. Stir well to coat the meat with the seasonings.
Step 5: Make the Sauce
Pour in the heavy cream and reduce heat to medium-low. Add the Velveeta cubes and stir until melted into a smooth sauce.
Step 6: Add Cheeses
Stir in the mozzarella and Parmesan cheeses, mixing until everything is melted and thickened into a creamy sauce.
Step 7: Combine Pasta with Sauce
Add the cooked penne pasta to the skillet. Toss to fully coat all pasta in the cheesy sauce.
Step 8: Final Touches
Taste and adjust with salt and pepper as needed. Let simmer for a couple more minutes to thicken further if desired.
Step 9: Serve
Serve hot, garnished with chopped parsley if using. Enjoy your meal!
How to Serve Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
Serving Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce can elevate your dining experience. This dish is not only rich and creamy but also bursting with flavor, making it perfect for various occasions.
Dinner Parties
- Pair with a garden salad for a refreshing contrast to the cheesy pasta.
- Serve with crusty garlic bread for a satisfying crunch.
Family Gatherings
- Offer alongside roasted vegetables to balance the richness of the dish.
- Present with a platter of sliced baguette for easy sharing.
Casual Meals
- Enjoy it with steamed broccoli for a healthy side.
- Serve with a light soup as an appetizer for a complete meal.
How to Perfect Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
Perfecting this recipe can enhance its taste and texture. Follow these simple tips to achieve the best results.
- Use fresh ingredients: Fresh garlic and high-quality cheeses make a significant difference in flavor.
- Don’t overcook pasta: Cook penne just until al dente; it will continue cooking when mixed with the sauce.
- Adjust seasoning wisely: Taste the sauce before serving, and adjust seasoning as needed for optimal flavor.
- Add veggies: Consider mixing in bell peppers or spinach for added nutrition and color.
- Let it rest: Allowing the dish to sit for a few minutes after cooking helps the flavors meld together.
Best Side Dishes for Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
Complementing your Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce with the right sides can enhance your meal. Here are some excellent suggestions.
- Caesar Salad: Crisp romaine lettuce and creamy dressing provide a refreshing contrast.
- Garlic Breadsticks: Soft and buttery breadsticks are perfect for scooping up leftover sauce.
- Roasted Asparagus: Lightly seasoned asparagus adds a touch of elegance and color to your plate.
- Coleslaw: A tangy coleslaw balances the richness of the pasta dish perfectly.
- Grilled Corn on the Cob: Sweet corn offers a delightful crunch that pairs well with creamy dishes.
- Stuffed Bell Peppers: These can be filled with rice or quinoa for an interesting twist on traditional sides.
Common Mistakes to Avoid
Cooking can be a delightful experience, but it’s easy to make mistakes. Here are some common pitfalls when preparing Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce.
- Skipping the seasoning – Failing to season your beef properly can lead to bland results. Make sure to thoroughly mix in the Cajun and Italian seasonings for a burst of flavor.
- Overcooking the pasta – Cooking the penne too long can result in mushy pasta. Follow the package instructions carefully and aim for al dente for the best texture.
- Not draining excess fat – Leaving excess fat from the beef can make your dish greasy. Always drain well after browning the meat to keep your sauce smooth and creamy.
- Adding cheese too quickly – If you add all the cheese at once, it may clump instead of melting smoothly. Incorporate each type of cheese gradually for a velvety sauce.
- Ignoring taste adjustments – Forgetting to taste and adjust seasoning can leave your dish unbalanced. Always sample before serving and tweak with salt or pepper as needed.

Storage & Reheating Instructions
Refrigerator Storage
- Store leftovers in an airtight container for up to 3 days.
- Allow the dish to cool completely before sealing to prevent condensation.
Freezing Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
- Freeze in an airtight container for up to 3 months.
- Consider portioning out servings for easier reheating later.
Reheating Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
- Oven – Preheat to 350°F (175°C) and bake covered for about 20 minutes until heated through.
- Microwave – Heat in short bursts, stirring between intervals, until hot throughout.
- Stovetop – Warm over medium-low heat, stirring frequently, adding a splash of cream if needed to restore creaminess.
Frequently Asked Questions
Here are some common questions about preparing Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce.
Can I use chicken instead of beef?
Yes! Substitute ground chicken for a lighter option, and follow the same cooking instructions.
What if I don’t have Velveeta cheese?
You can replace Velveeta with a mixture of cream cheese and shredded cheddar for a similar creamy texture.
How spicy is this Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce?
The spice level depends on your Cajun seasoning brand. Adjust according to your heat preference by using more or less seasoning.
Can I make this dish vegetarian?
Absolutely! Use plant-based ground meat or mushrooms, and consider swapping heavy cream with coconut milk or cashew cream for a creamy texture without meat.
Final Thoughts
Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce is a delightful meal that brings together rich flavors and comforting textures. This recipe is versatile—customize it by swapping proteins or adding vegetables like bell peppers or spinach. Give it a try; your taste buds will thank you!
Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
Indulge in the rich and creamy goodness of Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce—a dish that combines tender beef, aromatic garlic, and a blend of Cajun spices enveloped in a luscious cheese sauce. Perfect for family dinners or casual gatherings, this recipe is not only quick to prepare but also incredibly satisfying. With its delightful flavors and velvety texture, it promises to impress everyone at your table. Whether you’re looking for a comforting weeknight meal or a standout dish for special occasions, this creamy penne recipe is a must-try.
- Prep Time: 10 minutes
- Cook Time: 20 minutes
- Total Time: 30 minutes
- Yield: Serves 6
- Category: Main
- Method: Skillet
- Cuisine: American
Ingredients
- 1 lb ground beef
- 12 oz penne pasta
- 4 cloves garlic, minced
- 1 cup heavy cream
- 1 cup Velveeta cheese, cubed
- 1 cup shredded mozzarella cheese
- ½ cup grated Parmesan cheese
- 2 tablespoons butter
- 1 tablespoon Cajun seasoning
- 1 teaspoon Italian seasoning (optional)
- Salt and black pepper to taste
Instructions
- Cook the penne pasta according to package directions until al dente, then drain.
- In a skillet over medium heat, melt butter and sauté minced garlic until fragrant.
- Add ground beef, cooking until browned; drain excess fat.
- Stir in Cajun seasoning and optional Italian seasoning.
- Pour in heavy cream and reduce heat; add Velveeta, stirring until melted.
- Mix in mozzarella and Parmesan cheeses until smooth.
- Combine cooked pasta with the sauce, tossing to coat evenly.
- Adjust seasoning with salt and pepper before serving.
Nutrition
- Serving Size: 1 cup (240g)
- Calories: 550
- Sugar: 3g
- Sodium: 600mg
- Fat: 30g
- Saturated Fat: 15g
- Unsaturated Fat: 13g
- Trans Fat: 0g
- Carbohydrates: 45g
- Fiber: 3g
- Protein: 30g
- Cholesterol: 90mg




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